Do you want a general overview of US patent applications on histamine biosynthesis, or would you like me to help you find and summarize specific US patents/patent applications?
Here’s a quick primer and how you can search effectively:
What “histamine biosynthesis” patents might cover
- Methods to produce histamine in engineered organisms (e.g., microbes or cells) via histidine decarboxylase (HDC) or related pathways.
- Genes, enzymes, and expression constructs for histamine production (HDC genes, cofactor handling, promoter systems, host strains).
- Fermentation and purification processes to maximize histamine yield.
- Biosensors or assays for histamine production.
- Related work aimed at reducing unwanted histamine formation in foods (e.g., inhibiting HDC in spoilage bacteria) could also appear in this space, if framed around biosynthesis control.
How to search (start with these)
- Google Patents (recommended for quick public-frontend browsing)
- Search terms (combination works well):
- "histamine biosynthesis"
- "histidine decarboxylase"
- "histamine production"
- "biosynthesis of histamine"
- Then filter results to country: US (top left filter) to focus on US publications/applications.
- Look at publication numbers, dates, and assignees to gauge relevance and status (published vs granted).
- USPTO Patent Center
- Use advanced search with keywords like histamine, histidine decarboxylase, biosynthesis, production.
- Filter by US patent publications and consider checking status (pending vs granted).
- Espacenet (EPO) and WIPO Patentscope (for family context)
- Useful to find family members that include US filings.
- Suggested search refinements
- Focus on biological methods: include "biological production" or "recombinant host" with HDC.
- If you’re interested in applications, include terms like "method," "process," "production," "fermentation," "enzyme," "gene," "construct," "host."
- If you’re also curious about safety/food context, search for "histamine reduction" or "histamine regulation" in foods, then check if the document discusses biosynthesis control.
What I can do for you
- If you want, I can perform a targeted search and summarize US patent applications (assignees, publication numbers, dates, and a plain-language summary of the claims). I just need permission to look up current patent records, or you can share any specific publication numbers or assignees you already have.
- If you already have a few US patent application numbers, paste them here and I’ll summarize their claims and relevance to histamine biosynthesis.
Tell me:
- Do you want a quick overview, or a detailed pull of US patent publications on histamine biosynthesis?
- Any constraints (time window, granted vs published, specific assignees, or whether you only want biosynthesis in microorganisms vs. enzyme/gene claims)?