Mixing alcohol and Advil, a brand name for the drug ibuprofen, can have potential risks and side effects. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can help reduce pain, inflammation, and fever. When combined with alcohol, it can increase the risk of certain side effects.

One potential risk is an increased risk of stomach ulcers and internal bleeding [1]. Both alcohol and ibuprofen can irritate the lining of the stomach, and when used together, this effect may be amplified. This can lead to stomach ulcers, stomach pain, and in severe cases, internal bleeding.

Another risk is liver damage [1]. The liver is responsible for metabolizing both alcohol and ibuprofen, and when these substances are used together, it can put additional strain on the liver. This can increase the risk of liver damage, especially with long-term use.

Additionally, mixing alcohol and ibuprofen can increase the risk of kidney damage [1]. Both substances can affect kidney function, and using them together can increase this risk.

Finally, mixing alcohol and ibuprofen can also increase the risk of dizziness, drowsiness, and impaired judgment [1]. Both substances can cause these effects on their own, and when used together, it can increase the risk and severity of these effects.

It is important to note that these risks may vary depending on the individual, the amount of alcohol and ibuprofen consumed, and the frequency of use. If you have any concerns about mixing alcohol and ibuprofen, it is always best to speak with a healthcare provider.

Sources:
[1] "Mixing Ibuprofen and Alcohol." DrugPatentWatch.com, <https://www.drugpatentwatch.com/mixing-ibuprofen-and-alcohol/>.