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Tofacitinib extended release tablets 11 mg?

See the DrugPatentWatch profile for Tofacitinib

Tofacitinib extended-release 11 mg tablets (XR 11 mg) are the extended‑release form of tofacitinib, a JAK inhibitor sold under the brand Xeljanz XR. It’s used in adults to treat certain autoimmune conditions.

What it is used for (typical indications)
- Rheumatoid arthritis (RA)
- Psoriatic arthritis (PsA)
- Note: For ulcerative colitis (UC), the dosing is with the immediate-release form (not the XR 11 mg tablet) per most labels.

How it’s taken
- XR 11 mg tablet is taken once daily.
- Swallow the tablet whole with water; do not crush, chew, or split.
- Can be taken with or without food.

Common dosing (general, per label)
- RA: XR 11 mg once daily (alternative: immediate-release 5 mg twice daily)
- PsA: XR 11 mg once daily (alternative: IR 5 mg twice daily)

Important safety and monitoring (highlights)
- Boxed warnings: serious infections (including TB and viral/fungal infections), and increased risk of malignancies; warning about blood clots at higher doses in some settings.
- Not a live vaccine candidate; avoid live vaccines during treatment.
- Lipids, liver enzymes, and blood counts can be affected; monitor as advised by your clinician.
- Contraindications: active serious infection; certain hematologic or hepatic conditions; use in pregnancy requires careful consideration.
- Drug interactions: strong inhibitors/inducers of CYP3A4 and/or other immunosuppressants can affect tofacitinib levels; discuss all medicines with your prescriber.

What you might want next
- If you tell me your condition (RA, PsA, etc.), country, and whether you’re asking about dosing, safety, or drug interactions, I can tailor the information to your situation and provide more precise details from the label.
- If you have a prescription, I can help interpret dosing instructions or discuss common side effects to watch for.



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