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See the DrugPatentWatch profile for Tofacitinib
Tofacitinib extended-release 11 mg tablets (XR 11 mg) are the extended‑release form of tofacitinib, a JAK inhibitor sold under the brand Xeljanz XR. It’s used in adults to treat certain autoimmune conditions. What it is used for (typical indications) - Rheumatoid arthritis (RA) - Psoriatic arthritis (PsA) - Note: For ulcerative colitis (UC), the dosing is with the immediate-release form (not the XR 11 mg tablet) per most labels. How it’s taken - XR 11 mg tablet is taken once daily. - Swallow the tablet whole with water; do not crush, chew, or split. - Can be taken with or without food. Common dosing (general, per label) - RA: XR 11 mg once daily (alternative: immediate-release 5 mg twice daily) - PsA: XR 11 mg once daily (alternative: IR 5 mg twice daily) Important safety and monitoring (highlights) - Boxed warnings: serious infections (including TB and viral/fungal infections), and increased risk of malignancies; warning about blood clots at higher doses in some settings. - Not a live vaccine candidate; avoid live vaccines during treatment. - Lipids, liver enzymes, and blood counts can be affected; monitor as advised by your clinician. - Contraindications: active serious infection; certain hematologic or hepatic conditions; use in pregnancy requires careful consideration. - Drug interactions: strong inhibitors/inducers of CYP3A4 and/or other immunosuppressants can affect tofacitinib levels; discuss all medicines with your prescriber. What you might want next - If you tell me your condition (RA, PsA, etc.), country, and whether you’re asking about dosing, safety, or drug interactions, I can tailor the information to your situation and provide more precise details from the label. - If you have a prescription, I can help interpret dosing instructions or discuss common side effects to watch for.
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