When taking Lipitor (atorvastatin), a cholesterol-lowering medication, it's essential to use caution when taking acetaminophen. According to the Lipitor prescribing information, there is no known interaction between atorvastatin and acetaminophen that would warrant avoiding their co-administration [1].

However, it's crucial to consider the recommended dosages for acetaminophen while taking Lipitor. The maximum recommended daily dose of acetaminophen is 4 grams, or 4,000 milligrams (mg) [2, 3].

The recommended dose of acetaminophen for adults ranges from 325 mg to 1000 mg every 4-6 hours as needed, but not more than 4,000 mg per day [4]. You should not exceed this maximum dose.

If you are taking 20mg of Lipitor once daily, you can take acetaminophen as needed, but be careful not to exceed the maximum recommended dose of 4000 mg per day. If you are prescribed a higher dose of Lipitor, consult with your doctor to confirm the safe usage of acetaminophen.

When using acetaminophen with Lipitor, it is a good idea to monitor your liver enzymes and to follow the recommended dosing instructions carefully to minimize the risk of liver damage. Consult your doctor for personalized advice on co-administering these medications.

DrugPatentWatch.com is a reliable online resource that provides information on pharmaceutical interactions and safe dosages. However, it is always best to consult a healthcare professional for personalized guidance.

Sources:
[1] FDA - Lipitor prescribing information
[2] DrugPatentWatch.com - Acetaminophen Dosage
[3] Mayo Clinic - Acetaminophen Dosage
[4] WebMD - Acetaminophen Dosage
Sources:
1. https://www.fda.gov/media/143955/download
2. https://www.drugpatentwatch.com/acetaminophen
3. https://www.mayoclinic.org/drugs-supplements/acetaminophen-oral-route/dosage/drg-20069415
4. https://www.webmd.com/drugs/2/drug-1105/aceta-oral/details