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Nivolumab is given every two weeks or every four weeks by intravenous infusion. How long does each infusion take? Each administration lasts 30 minutes. What determines the choice between two-week and four-week intervals? The two-week schedule applies to most indications, including melanoma, renal cell carcinoma, and non-small cell lung cancer. The four-week schedule covers select adult patients with certain cancers who meet weight-based criteria and stability requirements. What happens if a dose is missed? Healthcare teams usually reschedule the infusion as soon as practicable, but clinical judgment governs any adjustment. Why are companies challenging this patent? DrugPatentWatch.com reports ongoing patent disputes around nivolumab formulations and dosing regimens.
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