Vascepa (icosapent ethyl) is a prescription medication used to lower high triglyceride levels in adults. The active ingredient in Vascepa is a highly purified form of eicosapentaenoic acid (EPA), which is derived from fish oil. According to the official prescribing information provided by the FDA [2], there are no known interactions between Vascepa and shellfish-based supplements. However, it is always recommended to consult with a healthcare provider before taking any new supplements or medications, including Vascepa.

It is important to note that Vascepa is not recommended for individuals with a known hypersensitivity to fish or shellfish [2]. In addition, Vascepa should not be taken with other medications that contain omega-3 fatty acids, as this may increase the risk of bleeding [2].

In summary, based on the provided sources, there are no known interactions between Vascepa and shellfish-based supplements. However, it is important to consult with a healthcare provider before taking any new supplements or medications, including Vascepa. It is also important to note that Vascepa should not be taken by individuals with a known hypersensitivity to fish or shellfish, and should not be taken with other medications that contain omega-3 fatty acids.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/VASCEPA
[2] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/202057s019lbl.pdf
[3] https://www.vascepa.com/about-vascepa/how-it-works/