What is vancomycin used for?

Vancomycin is a glycopeptide antibiotic used mainly for serious Gram-positive infections, especially when the organisms are resistant to other antibiotics.

Common uses
- Infections caused by MRSA (staph aureus that’s methicillin-resistant): bloodstream infections, endocarditis, osteomyelitis, septic arthritis, complicated skin/soft tissue infections, pneumonia (including hospital-acquired).
- Infections due to other susceptible Gram-positive bacteria (e.g., some streptococci and enterococci, though some enterococci may be resistant).
- C. difficile infection in the gut: oral vancomycin is used for C. difficile–associated diarrhea and colitis (not absorbed, acts in the GI tract).

Important notes
- IV vancomycin is used for systemic infections; oral vancomycin is used for GI infections like C. difficile.
- Not effective against most Gram-negative bacteria.
- Dosing and duration depend on the type and severity of infection and kidney function; trough level monitoring is common to balance efficacy and risk of kidney/ear toxicity.
- Rate of IV infusion matters: too fast can cause “red man” syndrome; typically infused slowly over at least an hour.
- Resistance can occur (e.g., VRE strains).

If you’re asking for a specific situation (e.g., infection type, patient age, kidney function), I can tailor the info. And always follow a clinician’s guidance with antibiotic use.