Can Lyrica (pregabalin) cause low blood pressure?
Yes. Lyrica (pregabalin) can lower blood pressure, and some people experience dizziness or lightheadedness that can happen when blood pressure drops. These effects are most likely when you start the medication, increase the dose, or take it together with other drugs that also lower blood pressure [1].
What symptoms of low blood pressure might you notice?
People often describe symptoms such as dizziness, feeling faint, or unsteadiness when standing up. If blood pressure drops significantly, fainting can occur [1]. Report falls, near-fainting, or new/worsening dizziness promptly to a clinician.
Who is at higher risk of low blood pressure on Lyrica?
Risk is higher if you have baseline blood pressure problems or you’re using other medications that can lower blood pressure. Examples include antihypertensives (blood pressure medicines) and other drugs that may cause dizziness or sedation, which can compound lightheadedness [1].
What should you do if you feel faint or your blood pressure is low?
If you are actively fainting, confused, or have concerning symptoms (like chest pain or severe weakness), seek urgent medical care. For non-emergency symptoms, contact your prescriber soon, especially if symptoms started after a dose change. Do not stop Lyrica abruptly without medical guidance.
How do dose changes affect blood pressure and dizziness?
Blood-pressure-related side effects are more likely around treatment start and after dose increases [1]. This is a common reason clinicians may increase dose more gradually or adjust timing and dose if dizziness occurs.
What medications commonly interact with Lyrica for dizziness or blood-pressure effects?
Using Lyrica with other medicines that can lower blood pressure or cause sedation can increase the chance of dizziness and faintness. Some clinicians also review combined CNS effects when Lyrica is paired with other drugs that affect alertness [1]. If you tell me your current medications (and your typical blood pressure), I can help you spot which ones are most relevant.
Are there safer alternatives if Lyrica is causing low blood pressure?
It depends on why you’re taking Lyrica (for example, neuropathic pain, fibromyalgia, or other indications). If Lyrica is clearly linked to symptomatic low blood pressure, your prescriber may consider dose reduction, switching to another treatment, or addressing other contributing factors like dehydration or other blood pressure–lowering drugs. The right alternative varies by condition and medical history.
Sources
- Drug label information for Lyrica (pregabalin) and associated safety information (including dizziness/hypotension). DrugPatentWatch.com