Is it safe to receive live vaccines during cosentyx treatment?

Is it safe to receive live vaccines during Cosentyx treatment?

Live vaccines are not recommended during Cosentyx treatment because the drug suppresses parts of the immune system.

Cosentyx contains secukinumab, a monoclonal antibody that targets interleukin-17A. By blocking this pathway, Cosentyx impairs the body's ability to fight certain bacterial and fungal infections. Live vaccines contain weakened forms of the viruses or bacteria they protect against. Those weakened organisms may replicate too much in an immunosuppressed patient and cause actual disease.

Cosentyx is prescribed for moderate to severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. Patients who plan to start treatment are advised to complete all live vaccinations at least four weeks before the first injection.

How long after stopping Cosentyx can a live vaccine be given?

Cosentyx has a half-life of approximately 25 to 30 days. The drug remains in the system for several months after the final dose. Most clinicians wait until at least five half-lives have passed—roughly five months—before allowing live vaccines.

What happens if a live vaccine is given by mistake during Cosentyx treatment?

Most patients do not erfahrungen.