What vaccines require schedule changes with cosentyx?

Schedule Changes with Cosentyx: Understanding the Interactions with Common Vaccines

Cosentyx, also known as secukinumab, is a biologic medication used to treat moderate to severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. It works by targeting and inhibiting the activity of certain proteins in the body that promote inflammation. When considering vaccination schedules, it's essential to understand how Cosentyx may interact with commonly administered vaccines.

When Should You Adjust the Schedule?

According to the Cosentyx prescribing information, live vaccines should be avoided while on Cosentyx treatment [1]. Live vaccines contain a weakened form of the virus, which can cause mild or asymptomatic infections in most people. However, individuals taking immunosuppressive therapies like Cosentyx are at a higher risk for developing serious infections.

Common Live Vaccines That May Conflict with Cosentyx

Some live vaccines that may require schedule adjustments or alternative vaccination strategies include:

* Mumps, measles, and rubella (MMR): People with weakened immune systems should avoid live vaccines like MMR while taking Cosentyx or any other immunosuppressive medication.
* Chickenpox (varicella): Live vaccines like varicella should be avoided, as the risk of developing shingles or chickenpox is higher in individuals taking immunosuppressive therapies.
* Oral poliovirus (OPV): OPV is a live vaccine that should be avoided in individuals with weakened immune systems.

Why Not Use Live Vaccines While on Cosentyx?

Cosentyx and other immunosuppressive medications can weaken the immune system, making it challenging to handle the weakened virus in live vaccines. Infection control measures are critical to preventing the spread of illness in these cases.

What About Inactivated Vaccines?

Inactivated vaccines contain killed or inactivated pathogens and are generally considered safe for individuals taking immunosuppressive medications, including Cosentyx [1]. Examples of inactivated vaccines include:

* Flu (inactivated influenza vaccine): This vaccine is safe for people taking Cosentyx or other immunosuppressive therapies.
* Tdap (tetanus, diphtheria, and pertussis): Tdap is an inactivated vaccine that can be administered while taking Cosentyx.

Consult Your Healthcare Provider

Consult your healthcare provider or a specialist in immunology or rheumatology if you have any questions or concerns regarding vaccination schedules while on Cosentyx. They will be able to provide personalized guidance based on your specific health needs and medical history.

References:

[1] Novartis. (2022). Cosentyx (secukinumab) Injection, for subcutaneous use. US Prescribing Information.