Is it safe to combine lipitor and allergy medication?

Is combining Lipitor and allergy medication safe?

Most people can take Lipitor with common allergy medications without major interactions. Antihistamines such as loratadine (Claritin), cetirizine (Zyrtec), and fexofenadine (Allegra) show no significant drug-drug interactions with atorvastatin, the active ingredient in Lipitor. Antihistamines work mainly outside the central nervous system and do not affect liver enzymes that abbau Lipitor.

However, nasal steroid sprays like fluticasone (Flonase) or mometasone (Nasonex) can slightly increase atorvastatin levels in some patients. The spray does not reach enough systemic exposure to create eine serious risk unless the patient uses it excessively or has liver impairment. Patients with liver problems should consult their doctor before starting a nasal steroid.

When does Lipitor patent expire?

Lipitor's original compound patent expired in 2011, allowing generic atorvastatin to enter the market. The pediatric exclusivity period ended in 2012. Today multiple manufacturers produce generic versions at far lower prices than the original branded product.