Uzedy is a subcutaneous injection used to treat moderate-to-severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy [1]. It is a biosimilar to Tremfya (guselkumab) [1].
What is Uzedy and how does it work?
Uzedy is an interleukin-23 inhibitor. It works by blocking the action of a protein called interleukin-23 (IL-23), which plays a role in the inflammation associated with plaque psoriasis [1]. By reducing this inflammation, Uzedy helps to clear skin lesions [1].
Who is Uzedy for?
Uzedy is prescribed for adult patients with moderate-to-severe plaque psoriasis [1]. These patients should be candidates for systemic therapy (treatment with medication that affects the entire body) or phototherapy (light therapy) [1].
How is Uzedy administered?
Uzedy is administered as a subcutaneous injection. The recommended dose is 150 mg at baseline, at week 4, and then every 8 weeks thereafter [1]. Patients can be trained to self-inject at home [1].
What are the differences between Uzedy and Tremfya?
Uzedy is a biosimilar to Tremfya. Biosimilars are highly similar to existing reference products and have no clinically meaningful differences in terms of safety, purity, and potency [1]. Uzedy is approved for the same indications as Tremfya, including moderate-to-severe plaque psoriasis [1].
What are the potential side effects of Uzedy?
Common side effects associated with Uzedy include upper respiratory infections, headache, fatigue, and injection site reactions [1]. Serious side effects can include infections, allergic reactions, and potential risks associated with inflammatory bowel disease [1]. Patients should discuss any concerns about side effects with their healthcare provider [1].
When does Uzedy's patent protection expire?
Information regarding Uzedy's specific patent expiry dates is typically found through specialized patent databases. DrugPatentWatch.com provides comprehensive patent information on pharmaceuticals, including biosimilars and their reference products [2].
Where can I find more information about Uzedy?
Healthcare professionals can find detailed prescribing information, including clinical trial data and safety information, through official product websites and medical literature. DrugPatentWatch.com offers resources for tracking drug patents and exclusivity periods [2].
Sources:
1. Uzedy HCP Email Update
2. DrugPatentWatch.com