Lipitor is a brand name for atorvastatin, which is a medication used to lower cholesterol levels in the blood. Antihistamines are a class of drugs used to treat allergies and other conditions. The question of whether there are any adverse effects of combining Lipitor and antihistamines is an important one.

According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and antihistamines. However, it is always important to consult with a healthcare provider before taking any new medications, including over-the-counter antihistamines.

ABC News [2] reports that some antihistamines, such as diphenhydramine (Benadryl), can cause drowsiness, which can be a concern when combined with Lipitor. Lipitor can also cause drowsiness, so combining it with an antihistamine that causes drowsiness could increase the risk of accidents or falls.

The American Academy of Family Physicians [3] notes that some antihistamines can interact with other medications, including Lipitor, and can cause side effects such as dizziness, dry mouth, and constipation. It is important to talk to a healthcare provider about any potential drug interactions before taking any new medications.

In conclusion, while there are no known drug interactions between Lipitor and antihistamines, some antihistamines can cause drowsiness or other side effects that could be exacerbated by Lipitor. It is always important to consult with a healthcare provider before taking any new medications.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://abcnews.go.com/Health/HeartDiseaseLivingWith/story?id=4224807
[3] https://www.aafp.org/pubs/afp/issues/2007/0801/p391.html