There are potential drug interactions between Lipitor (atorvastatin) and antihistamines. According to Drugs.com, combining Lipitor with allergy relief tablets containing antihistamines may increase the risk of side effects such as dizziness, drowsiness, and difficulty concentrating. The severity of these side effects can vary depending on the specific antihistamine being used. It is recommended that patients taking Lipitor should consult with their healthcare provider before taking any antihistamines or other medications to avoid potential drug interactions.

In addition, Verywell Health notes that statins such as Lipitor can interact with a variety of other medications, including antibiotics, antifungal drugs, and blood thinners. These interactions can affect the way that Lipitor is metabolized in the body, potentially leading to increased levels of the drug in the bloodstream and an increased risk of side effects. Patients taking Lipitor should inform their healthcare provider of all medications they are taking to avoid potential drug interactions.

Overall, while there are potential drug interactions between Lipitor and antihistamines, these interactions can be managed with proper medical supervision. Patients taking Lipitor should consult with their healthcare provider before taking any new medications to ensure that they are safe to use together.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.drugs.com/drug-interactions/allergy-relief-tablets-with-atorvastatin-1486-14544-276-0.html
[3] https://www.verywellhealth.com/statin-side-effects-and-drug-interactions-698202