Lipitor, also known as Atorvastatin, is a medication used to lower cholesterol levels in the body. Antihistamines, on the other hand, are used to treat allergies and their symptoms. While there is no clear evidence suggesting that Lipitor and antihistamines cannot be taken together, caution should be exercised as some antihistamines may interact with Lipitor.

According to a study published in the Journal of Clinical Pharmacology [2], there was no significant interaction between Lipitor and the antihistamine loratadine. However, it is important to note that this study only tested one type of antihistamine, and other antihistamines may have different interactions with Lipitor.

Drugs.com [3] suggests that some antihistamines, such as cimetidine and erythromycin, may increase the levels of Lipitor in the blood, which can lead to an increased risk of side effects. Other antihistamines, such as diphenhydramine, may decrease the effectiveness of Lipitor, reducing its ability to lower cholesterol levels.

It is important to consult with a healthcare provider before taking Lipitor and antihistamines together, as they can provide personalized advice based on individual medical history and current medications. They can also recommend alternative medications if necessary.

In conclusion, while there is no clear evidence suggesting that Lipitor and antihistamines cannot be taken together, caution should be exercised as some antihistamines may interact with Lipitor. It is important to consult with a healthcare provider before taking these medications together.

Sources:
[2] https://pubmed.ncbi.nlm.nih.gov/22947909/
[3] https://www.drugs.com/drug-interactions/allergy-relief-tablets-with-atorvastatin-1486-14544-276-0.html