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See the DrugPatentWatch profile for Magnesium
Magnesium aluminometasilicate is a porous, amorphous magnesium aluminum silicate used as a pharmaceutical excipient. It’s commonly sold under brand names like Neusilin (e.g., US2, US3). Key points: - What it is: a high-surface-area, porous silicate mineral that can adsorb liquids and drugs. - Primary roles in tablets/c capsules: - disintegrant: helps tablets break apart in the GI tract - adsorbent/moisture control: binds water and liquids to improve stability and flow - carrier for poorly soluble drugs or liquids (used in liquisolid systems) - glidant/flow aid: improves powder flow and compressibility - Why it’s used: enhances dissolution of poorly soluble drugs, improves tablet manufacture (flow, compression), and can enable liquid formulations to be turned into solids. - Safety and regulatory: considered an inert pharmaceutical excipient with low systemic absorption; aluminum content is low; approved for use in many products (check the specific product’s data sheet and regulatory status for your region). - Common grades: Neusilin US2, Neusilin US3 (different surface area and pore characteristics for various formulations). If you want, tell me the context (e.g., optimizing a tablet formulation, solubility enhancement, regulatory questions), and I can tailor the guidance (including typical loading ranges and exact grade recommendations from manufacturer datasheets).
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