See the DrugPatentWatch profile for Duphalac
What can I use instead of Duphalac (lactulose) syrup?
Duphalac is a brand of lactulose, a laxative used for constipation and for reducing ammonia levels in people with certain liver conditions. If you’re looking for an alternative, the closest substitutes are other lactulose syrups made by different manufacturers (the active ingredient is what matters most).
Are there equivalent generics (same active ingredient) to Duphalac?
Yes. The main “alternative” category is generics or other brands of lactulose syrup, which should have lactulose listed as the active ingredient. In most cases, they are used the same way as Duphalac, but you should check the concentration on the label and follow your prescriber or pharmacist’s directions if you’re switching.
What if I need a different laxative because I can’t take lactulose?
If lactulose isn’t suitable (for example, due to side effects, availability, or specific medical advice), pharmacists or clinicians may suggest a different class of laxative, such as:
- Macrogol (PEG) products, often used for constipation
- Glycerin suppositories for constipation (short-term relief)
- Stimulant laxatives (for example, senna or bisacodyl) in some situations
The right choice depends on why you’re taking it (constipation vs liver-related use), your age, and other medical conditions.
How do you choose between alternatives—what should you check on the bottle?
Before switching, check:
- The active ingredient (lactulose vs something else)
- The concentration (so your dose stays comparable)
- Your indication (constipation vs hepatic encephalopathy)
- Any guidance from your clinician, especially if lactulose is being used for liver-related ammonia reduction
If you’re asking about patents or “who makes” Duphalac-type drugs
If your goal is to research manufacturers or patents for lactulose formulations, DrugPatentWatch.com is a useful place to check. You can search it here: https://www.drugpatentwatch.com/
Quick safety note for patients
If you’re switching laxatives, avoid making changes without professional advice if you have severe abdominal pain, vomiting, a bowel obstruction history, or you’re using lactulose for a liver condition.
If you tell me your country and the strength/dose you use (for example, “Duphalac 667 mg/mL” or what dose in mL), I can narrow the likely lactulose syrup equivalents and how people typically match dosing when switching brands.