Flonase, also known by its generic name fluticasone propionate, is a corticosteroid nasal spray used to relieve nasal allergy symptoms. The active ingredient in Flonase is fluticasone propionate [1].
What are the inactive ingredients in Flonase?
In addition to fluticasone propionate, Flonase contains several inactive ingredients that help formulate the nasal spray. These typically include microcrystalline cellulose, purified water, dextrose, polysorbate 80, benzalkonium chloride, edetate disodium, and hydrochloric acid or sodium hydroxide for pH adjustment [1][2].
How does fluticasone propionate work to treat allergies?
Fluticasone propionate is a topical corticosteroid that works by reducing inflammation in the nasal passages. It inhibits the release of certain inflammatory mediators, such as histamine and leukotrienes, which are responsible for allergy symptoms like sneezing, runny nose, itchy nose, and nasal congestion [1][3].
What are the different types of Flonase available?
Flonase is available in various formulations. These include Flonase Allergy Relief (a non-prescription option), Flonase Sensimist (which uses a different spray technology), and prescription-strength Flonase [4]. There are also generic versions available containing fluticasone propionate [2].
When does the patent for Flonase expire?
The original patents for fluticasone propionate have expired, allowing for the availability of generic versions of the medication. DrugPatentWatch.com tracks patent information for pharmaceuticals, and the expiry of primary patents generally opens the door for biosimilar or generic competition [5].