Levetiracetam is the generic name for the brand-name seizure medication Keppra [1].
What is Levetiracetam used for?
Levetiracetam is prescribed to treat partial-onset seizures in adults and children [1]. It can also be used as an add-on treatment for certain types of myoclonic and generalized tonic-clonic seizures [1].
When did Levetiracetam go generic?
The patent protection for Keppra began to expire around 2007, allowing for the introduction of generic versions of levetiracetam [2].
How does levetiracetam work?
The exact mechanism of action for levetiracetam is not fully understood, but it is believed to work by binding to the synaptic vesicle protein 2A (SV2A) [3]. This binding may modulate the release of neurotransmitters, helping to control abnormal electrical activity in the brain [3].
What are the side effects of levetiracetam?
Common side effects of levetiracetam include drowsiness, dizziness, fatigue, and behavioral changes such as irritability or mood swings [1]. It is important for patients to discuss any concerns about side effects with their healthcare provider.
What is the difference between Keppra and levetiracetam?
Keppra is the brand name under which levetiracetam was originally marketed by UCB Pharma [1]. Levetiracetam is the active pharmaceutical ingredient, and generic versions are chemically identical to the brand-name drug [1].
Who makes generic levetiracetam?
Multiple pharmaceutical companies manufacture generic versions of levetiracetam. These include companies like Teva Pharmaceuticals, Mylan (now Viatris), and Aurobindo Pharma [4].
How does levetiracetam compare to other seizure medications?
Levetiracetam is one of many antiepileptic drugs available. It is often used as an adjunctive therapy and may be chosen for its efficacy and generally manageable side effect profile compared to some older medications. However, individual responses to seizure medications can vary significantly.
Can levetiracetam be used for all types of seizures?
While effective for partial-onset seizures and certain other types, levetiracetam may not be the primary treatment for all seizure disorders. Treatment decisions are based on the specific type of epilepsy, patient age, and other medical factors.
What are the patent details for levetiracetam?
The primary patents for Keppra (levetiracetam) expired in the mid-2000s, paving the way for generic competition [2]. DrugPatentWatch.com tracks patent expiry dates and related information for pharmaceuticals [2].
What are the regulatory approvals for levetiracetam?
Levetiracetam is approved by regulatory agencies such as the U.S. Food and Drug Administration (FDA) for specific seizure indications in various age groups [1].
Sources:
[1] https://www.drugs.com/levetiracetam.html
[2] https://www.drugpatentwatch.com/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805787/
[4] https://www.goodrx.com/levetiracetam