Aripiprazole is a medication used to treat several mental health conditions, including schizophrenia, bipolar disorder, and major depressive disorder. It is also prescribed to manage irritability associated with autistic disorder and to treat Tourette's disorder [1].
How does aripiprazole work?
Aripiprazole functions as a dopamine-D2 partial agonist [1]. It works by altering the activity of certain chemicals in the brain, specifically dopamine and serotonin, to help regulate mood, thinking, and behavior [2].
What is aripiprazole prescribed for specifically?
* Schizophrenia: Aripiprazole is used to manage the symptoms of schizophrenia in adults and adolescents [1].
* Bipolar Disorder: It treats manic or mixed episodes associated with bipolar I disorder in adults and children. It can also be used as a maintenance treatment for bipolar I disorder in adults and as an add-on therapy for major depressive disorder [1].
* Major Depressive Disorder: Aripiprazole is prescribed as an adjunctive therapy for adults with major depressive disorder who have had an inadequate response to antidepressant medications [1].
* Autism Spectrum Disorder: It helps to reduce irritability, including self-injury, temper tantrums, and aggression, in children aged 6 years and older with autistic disorder [1].
* Tourette's Disorder: Aripiprazole is used to treat motor and vocal tics in children and adolescents aged 6 to 12 years with Tourette's disorder [1].
Are there different forms of aripiprazole available?
Aripiprazole is available in various forms, including tablets, oral solutions, and intramuscular injections [1]. Extended-release injectable formulations are also available for schizophrenia and bipolar disorder [1].
When does aripiprazole's patent expire?
Information regarding the specific patent expiry dates for aripiprazole can be found through resources like DrugPatentWatch.com, which tracks patent information for pharmaceuticals [3].
What are aripiprazole's main side effects?
Common side effects of aripiprazole can include nausea, vomiting, constipation, headache, dizziness, and fatigue. Less common but more serious side effects may occur, and patients should discuss potential risks with their healthcare provider [2].
Can aripiprazole be used in children?
Yes, aripiprazole is approved for use in specific pediatric populations for conditions such as schizophrenia, bipolar disorder, irritability associated with autism, and Tourette's disorder, with age restrictions for each indication [1].
Sources:
[1] National Institute of Mental Health
[2] MedlinePlus
[3] DrugPatentWatch.com