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What is Slo-Niacin, and what are its side effects? Slo-Niacin, also known as niacin extended-release, is a prescription medication used to treat high cholesterol and preeclampsia [1]. It is a form of vitamin B3 that helps lower triglyceride levels and raise high-density lipoprotein (HDL) cholesterol. However, like many medications, it can cause side effects, some of which can be quite uncomfortable. Can Slo-Niacin cause flushing? Yes, one of the most common side effects of Slo-Niacin is flushing or skin reddening. This occurs because the medication widens blood vessels, allowing more blood to flow to the skin's surface and causing a warm, flushed sensation [2]. According to the prescribing information, flushing can be severe and may be accompanied by headaches, itching, sweating, and dizziness. How to manage Slo-Niacin-induced flushing While some patients may experience only mild flushing, others may find it severe and debilitating. If you're taking Slo-Niacin, there are a few things you can do to reduce the risk of flushing: * Take your medication at bedtime, as this may help minimize flushing during the day. * Avoid drinking alcohol while taking Slo-Niacin, as this can increase the risk of flushing. * Consider taking an aspirin or antihistamine as directed by your healthcare provider to help alleviate symptoms. Long-term risks associated with flushing Prolonged or severe flushing can increase the risk of other side effects, such as skin thickening and discoloration. In rare cases, people may experience serious skin reactions, such as Stevens-Johnson syndrome or toxic epidermal necrolysis [3]. If you experience any unusual skin symptoms, seek medical attention immediately. Alternatives to Slo-Niacin If you're experiencing severe flushing or other side effects from Slo-Niacin, talk to your healthcare provider about alternative medications or treatment options [4]. There are many other cholesterol-lowering medications available, and your healthcare team can help you find one that's right for you. [1] https://www.drugs.com/mtm/slo-niacin-extended-release.html [2] https://www.everydayhealth.com/drugs-slo-niacin/niacin-extended-release-side-effects/#1 [3] https://www.drugs.com/side-effects/slo-niacin-extended-release.html [4] A study, comparing side effects of drugs like Slo-Niacin and others found here; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751773/.
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