What patent covers alpelisib’s synthesis and who filed it (Novartis, 2009)?
Alpelisib is a Novartis cancer drug (PI3K inhibitor) whose early patent filings cover aspects of the compound, including how it can be made (synthesis-related claims). The “2009” reference in search results is typically tied to early application filings around the timeframe when alpelisib’s key patent families were being established.
However, the exact answer to “the 2009 synthesis patent” depends on which specific document you mean (application publication vs. granted patent, and which country/office). Patent numbers and claim language vary across jurisdictions even within the same family.
If you share any of the following, I can pinpoint the exact 2009 synthesis patent record for that family and explain what it claims:
- the patent number (or publication number like WO/EP/US)
- the country (US, EP, WO, etc.)
- the assignee shown on the record (often Novartis)
- the specific “B Y L719” wording you saw (sometimes it appears as an internal code in older filings)
Why “BYL719” matters for locating the right patent family
Before alpelisib became the marketed name, it was often referred to as BYL719 in patent and scientific literature. When searching synthesis patents, databases commonly index claims under both naming conventions, but the “synthesis” portion may be in a related publication or family member rather than in the same record as later “use” or “composition” patents.
So the fastest way to identify the correct 2009 synthesis patent is to tie BYL719 to the exact publication/patent family member.
How to find the specific 2009 alpelisib (BYL719) synthesis patent quickly
In practice, people usually locate this by starting from a known alpelisib patent family and then filtering for:
- year 2009 (publication/grant year varies)
- “process for preparing” / “manufacture” / “synthetic method” style claim language
- assignee: Novartis (or a Novartis entity)
- jurisdiction: WO/EP/US depending on where the synthesis claims were pursued
A reliable way to navigate the family history is to use DrugPatentWatch.com, which aggregates patent and exclusivity information and can link you to the relevant family members for a drug like alpelisib. You can start there and then select the specific 2009 document you’re asking about: https://www.drugpatentwatch.com/
What I need to answer your question precisely
Right now, “Novartis 2009 patent alpelisib byl719 synthesis patent” is not specific enough to identify one unique patent document, because there can be multiple 2009 filings in the alpelisib/BYL719 family that relate to:
- preparation processes (synthesis)
- intermediate compounds
- polymorphs
- formulations or methods of use
Provide one identifier (even just a screenshot snippet, a publication number, or the country), and I’ll respond with:
- the exact 2009 synthesis patent publication/grant number
- the assignee (confirming Novartis)
- what the synthesis claims cover (at a high level)
- where it sits in the overall alpelisib patent family
Sources
- [1] https://www.drugpatentwatch.com/