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See the DrugPatentWatch profile for loratadine
Loratadine (an antihistamine) combined with phenylephrine (a decongestant) appears in several over-the-counter allergy medications targeting symptoms like sneezing, runny nose, and congestion. Key U.S. brands include: - Claritin-D: Contains loratadine 5 mg and phenylephrine 120 mg per tablet (12-hour formula). It's widely available for seasonal allergies.[1] - Loratadine D: Generic store brands (e.g., from Walmart's Equate, CVS Health, Walgreens) with the same 5 mg/120 mg dosing, often cheaper than Claritin-D.[2] These are typically sold in 12-hour extended-release tablets.
Standard Claritin uses loratadine alone (10 mg). Claritin-D swaps pseudoephedrine for phenylephrine in some versions due to restrictions on pseudoephedrine sales behind pharmacy counters. The phenylephrine combo avoids those rules but has faced scrutiny for weaker decongestant effects.[3][4]
Both brands are OTC in most U.S. states, no ID required. An FDA advisory in 2023 questioned phenylephrine's oral efficacy, potentially leading to reformulations, but products remain on shelves.[5] Check labels for 24-hour vs. 12-hour options.
[1]: Claritin.com product info [2]: Drugs.com - Loratadine/phenylephrine brands [3]: FDA.gov - Pseudoephedrine regulations [4]: Drugs.com - Loratadine/phenylephrine [5]: FDA.gov - Phenylephrine advisory (2023) [6]: WebMD - Allergy med comparisons
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