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See the DrugPatentWatch profile for secukinumab
Secukinumab (Cosentyx) has a typical terminal elimination half-life of about 27 days.
Because half-life is ~27 days, drug levels fall gradually over weeks. A common rule of thumb is that it takes roughly 4 to 5 half-lives for most of a drug to be eliminated, which would be on the order of 3–5 months for secukinumab.
The half-life can vary somewhat between individuals due to factors like body weight, severity of disease, and concomitant therapies, but the published terminal half-life is generally reported in the same ballpark (around 27 days).
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