How should novarel be stored after reconstitution?

How to Store NovoLog After Reconstitution

NovoLog (insulin aspart) is a rapid-acting insulin analog supplied as a clear, colorless solution in vials, cartridges, or prefilled pens. After reconstitution isn't typically needed for NovoLog, as it's ready-to-use—no mixing or reconstitution required per the prescribing information.[1]

Store unopened NovoLog:
- Refrigerated at 36°F to 46°F (2°C to 8°C).
- Do not freeze; discard if frozen.

Store opened/in-use NovoLog:
- At room temperature up to 86°F (30°C) for up to 28 days.
- Avoid direct heat, sunlight, or excessive temperatures.
- Do not refrigerate opened product.

What If It's a Vial and Looks Concentrated?

NovoLog vials are U-100 strength and pre-diluted. If cloudiness or particles appear (rare), discard—do not attempt reconstitution. Always inspect visually before use.[1]

Storage for NovoLog FlexPen or Cartridges

Same rules apply:
- Unopened: Refrigerate.
- In-use: Room temperature ≤28 days; do not store in fridge after first use.
- Keep pen cap on to protect from light.[1]

Risks of Improper Storage

Heat exposure above 86°F shortens potency; refrigeration of opened product causes precipitation. Always date opened product. Discard after 28 days or if discolored.[1]

Comparison to Other Insulins

Unlike NPH (requires mixing) or some compounded insulins, NovoLog skips reconstitution. Humalog (lispro) follows identical storage: 28 days at ≤86°F once opened.[2]

[1]: NovoLog Prescribing Information (Novo Nordisk)

[2]: Humalog Prescribing Information (Eli Lilly)