Alcohol consumption can potentially affect the effectiveness of cholesterol-lowering drugs, including statins [3]. Statins are a class of drugs that work by blocking the production of cholesterol in the liver. Alcohol can increase the risk of liver damage, and taking statins along with alcohol may increase the risk of liver damage [2]. Additionally, alcohol can also increase the risk of muscle damage or myopathy when taken with statins [3].

Other cholesterol-lowering drugs, such as bile acid sequestrants and ezetimibe, are not typically affected by alcohol consumption [2]. However, it is still important to consult with a healthcare provider before combining any medication with alcohol.

It is worth noting that alcohol itself can also have an impact on cholesterol levels. Moderate alcohol consumption may increase levels of high-density lipoprotein (HDL) or "good" cholesterol, while heavy alcohol consumption can increase levels of low-density lipoprotein (LDL) or "bad" cholesterol [2].

In summary, alcohol consumption can potentially affect the effectiveness and safety of statins, but is unlikely to affect other cholesterol-lowering drugs. It is important to consult with a healthcare provider before combining any medication with alcohol, and to be mindful of the potential impact of alcohol on cholesterol levels.

Sources:
[2] Drugs.com. (2021). Cholesterol Medications and Alcohol. Retrieved from https://www.drugs.com/article/cholesterol-medications-alcohol.html
[3] Medical News Today. (2018). Statins and Alcohol: Risks and Side Effects. Retrieved from https://www.medicalnewstoday.com/articles/statins-and-alcohol