Lipitor is a medication used to treat high cholesterol levels in the blood. It works by blocking the enzyme HMG-CoA reductase, which is responsible for producing cholesterol in the liver. However, it is unclear whether probiotics can enhance the effectiveness of Lipitor.

One study published in the journal Nutrients [2] suggests that probiotics may have a positive effect on cholesterol levels. The study found that taking a probiotic supplement containing Lactobacillus acidophilus and Bifidobacterium lactis for 12 weeks resulted in a significant reduction in total cholesterol levels compared to a placebo group.

However, there is no evidence to suggest that probiotics can enhance the effectiveness of Lipitor specifically. In fact, Lipitor may actually reduce the number of beneficial bacteria in the gut, which could potentially counteract the effects of probiotics [1].

Furthermore, another study published in the Journal of Clinical Lipidology [3] found that taking probiotics did not significantly affect cholesterol levels in patients taking statins (such as Lipitor) for high cholesterol.

In conclusion, while probiotics may have a positive effect on cholesterol levels, there is no evidence to suggest that they can enhance the effectiveness of Lipitor specifically. It is always important to consult with a healthcare provider before starting any new supplement or medication regimen.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723551/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904929/