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See the DrugPatentWatch profile for Zolpidem
Zolpidem tartrate 5 mg tablets are a prescription medication primarily used to treat short‑term insomnia (difficulty falling asleep). The tablets are usually taken orally right before bedtime, and the drug works quickly (onset in 15–30 min). | Item | Details | |------|---------| | Typical adult dose | 5 mg once nightly before bed. For adults ≥55 years or those with liver impairment, the usual dose is 3.75 mg. | | How it works | Zolpidem is a “non‑benzodiazepine hypnotic” that binds to the benzodiazepine site of the GABA‑A receptor, enhancing inhibitory neurotransmission and producing sedative‑hypnotic effects. | | Common brand names | Ambien (generic zolpidem tartrate), Ambien CR (controlled‑release), and generic equivalents. | | Key side‑effects | Drowsiness, dizziness, headache, dry mouth, gastrointestinal upset, and, in rare cases, vivid dreams or sleep‑walking. | | Special precautions | 1. Potential for dependence – use the lowest effective dose for the shortest duration (usually ≤ 2–4 weeks). 2. Cognitive/psychomotor impairment – avoid driving or operating heavy machinery for 24 h after taking the drug. 3. Alcohol – must be avoided because of additive CNS depression. 4. Pregnancy/breastfeeding – generally contraindicated; consult a healthcare provider. | | Drug interactions | Be cautious with other CNS depressants (opioids, benzodiazepines, alcohol, antihistamines). Certain CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) can increase zolpidem levels. | | Contraindications | Severe sleep apnea, hypersensitivity to zolpidem or any component, and severe hepatic impairment. | | What to do if you miss a dose | Skip the missed dose; do not double the next dose. | ---
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