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Antihistamine loratadine?

See the DrugPatentWatch profile for loratadine

Loratadine is a widely used, non-sedating second‑generation antihistamine. It helps relieve sneezing, itchy or runny nose, itchy eyes, and hives by blocking histamine at H1 receptors.

Key points
- What it treats: Allergic rhinitis (hay fever) symptoms and hives (urticaria).
- How it works: Blocks histamine receptors with less brain penetration, so it usually causes less drowsiness than older antihistamines.

Typical dosing (adults and children older than 12)
- 10 mg once daily by mouth.
- Forms: tablets (10 mg), orally disintegrating tablets (10 mg), syrup (5 mg/5 mL).
- For children:
- 6–11 years: 10 mg once daily.
- 2–5 years: 5 mg once daily.
- 12 years and up: 10 mg once daily.

Onset and duration
- Starts to work within 1–3 hours for many people.
- Effects last about 24 hours.

Safety and common side effects
- Generally well tolerated.
- Common: headache, fatigue or drowsiness (less than with first-generation antihistamines), dry mouth.
- Rare: stomach upset, dizziness.
- Caution with severe liver or kidney disease; talk with a clinician about dose adjustments if needed.

Interactions and precautions
- Alcohol can enhance sedative effects (though loratadine is less sedating).
- Some drug interactions can raise loratadine levels (notably certain strong CYP3A4 inhibitors such as ketoconazole or certain macrolide antibiotics). If you’re taking other meds, check with a healthcare provider.
- Pregnancy and breastfeeding: consult a clinician. Loratadine is often considered compatible, but you should confirm with your provider.

Additional notes
- Over-the-counter brand names include Claritin and Alavert (and generic versions). There are combination products with pseudoephedrine (Claritin-D) which can raise blood pressure or cause insomnia.

If you’d like, tell me your age, any other medicines you take, and whether you have liver/kidney issues. I can tailor dosing and safety info to you. Or I can answer a specific question you have about loratadine.



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