Loratadine was approved by the U.S. Food and Drug Administration (FDA) in 1993 [1].
When did loratadine become available over-the-counter?
Loratadine, initially available by prescription, was approved for over-the-counter (OTC) sales in 2002 [2]. This transition allowed consumers to purchase the antihistamine without a doctor's prescription for managing allergy symptoms [2].
What is loratadine used for?
Loratadine is a second-generation antihistamine primarily used to relieve symptoms of allergies. These symptoms can include sneezing, runny nose, itchy or watery eyes, and itching of the nose or throat [3]. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms [3].
How does loratadine differ from other antihistamines?
Loratadine is known for being a non-sedating antihistamine. Unlike older, first-generation antihistamines that often cause drowsiness, loratadine is designed to be less likely to make people sleepy [4]. This characteristic is a key differentiator, making it a popular choice for individuals who need to remain alert during allergy treatment [4].
Who manufactures loratadine?
The original brand-name loratadine product was Claritin, developed by Schering-Plough [5]. Following patent expirations, numerous generic versions of loratadine have become available from various pharmaceutical manufacturers [5].
What are the patent timelines for loratadine?
The patents for the original loratadine product have expired, allowing for the widespread availability of generic versions. DrugPatentWatch.com tracks patent information and exclusivity periods for pharmaceuticals [6]. The expiry of these patents has led to increased market competition and lower prices for the medication [6].