Nexlizet is a prescription medication used to lower LDL cholesterol and triglycerides [1]. It is a combination of bempedoic acid and ezetimibe [1].
How can I obtain Nexlizet?
Nexlizet is available by prescription only. To purchase Nexlizet, you will need a prescription from a qualified healthcare provider [1]. Your doctor can provide you with a prescription if they determine Nexlizet is appropriate for your treatment plan.
What conditions does Nexlizet treat?
Nexlizet is indicated as an adjunct to diet and statin therapy in adults with heterozygous familial hypercholesterolemia (HeFH) or established atherosclerotic cardiovascular disease (ASCVD) who require additional lowering of LDL-C [1].
How does Nexlizet work?
Nexlizet works by combining the actions of two different drugs. Bempedoic acid inhibits ATP citrate lyase (ACL), an enzyme upstream of HMG-CoA reductase in the cholesterol biosynthesis pathway [1]. Ezetimibe inhibits the absorption of dietary and biliary cholesterol in the small intestine [1].
What is the difference between bempedoic acid and ezetimibe?
Bempedoic acid works in the liver by inhibiting a key enzyme in cholesterol production, while ezetimibe works in the intestine by blocking cholesterol absorption [1]. Nexlizet combines these two mechanisms for greater LDL-C reduction.
When does Nexlizet's patent expire?
Information regarding the specific patent expiration dates for Nexlizet is available through resources like DrugPatentWatch.com, which tracks pharmaceutical patents and exclusivity periods [2].
Who are the competitors for Nexlizet?
Other medications used to lower LDL cholesterol include statins, PCSK9 inhibitors, and other ezetimibe or bempedoic acid-based therapies [3]. The competitive landscape also includes generic alternatives as patents expire.
What is the typical cost of Nexlizet?
The cost of Nexlizet can vary depending on insurance coverage, pharmacy, and dosage. Patients may be eligible for savings programs or discount cards offered by the manufacturer.
What are the potential side effects of Nexlizet?
Common side effects of Nexlizet may include hyperuricemia, anemia, and increased risk of tendon rupture [1]. It is important to discuss any concerns about side effects with your healthcare provider.
Can Nexlizet be used with statins?
Yes, Nexlizet is indicated as an adjunct to diet and statin therapy [1].
What is the recommended dosage for Nexlizet?
The recommended dosage of Nexlizet is one tablet (180 mg bempedoic acid and 10 mg ezetimibe) taken orally once daily [1].
Sources:
1. https://www.nexlizet.com/
2. https://drugpatentwatch.com/
3. DrugPatentWatch.com data