Dupixent shot price?

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Dupixent (dupilumab) – typical price range (as of mid‑2026)

Item	Typical U.S. Cost (list price)	Notes
First‑dose injection (600 mg)	≈ $5,600	600 mg is the loading dose given at the start of therapy.
Subsequent injections (300 mg)	≈ $3,000 – $4,000 per injection	300 mg is the maintenance dose given every 2 weeks.
Monthly cost (two injections)	≈ $6,000 – $8,000	Rough estimate based on the above per‑dose range.
Annual cost	≈ $72,000 – $96,000	Approximate yearly spending for a patient on a typical two‑per‑month schedule.

Manufacturer’s list price is set by Roche (the company that markets Dupixent) and is often cited in drug pricing databases (e.g., CMS Medicare Part D, Red Book).
Insurance: Most commercial and Medicare Part D plans negotiate discounts or rebates, so the average patient’s out‑of‑pocket cost is usually lower than the list price.
Patient assistance: The Dupixent Patient Assistance Program (PAP) offers up to a 75‑% discount for patients who qualify, which can significantly reduce the actual cost.
Pharmacy savings: Some specialty pharmacies offer additional copay help or “step‑in” discounts; these vary widely.

List price is roughly $3,000–$4,000 per 300 mg maintenance dose.
The first dose is typically 600 mg, costing about $5,600 at the list price.
Real‑world costs depend heavily on insurance coverage, negotiated rebates, and patient assistance programs.
If you’re considering Dupixent, check with your pharmacy or insurer for the exact copay or coinsurance you’ll owe. If it’s too expensive, ask your prescriber about the PAP or other cost‑sharing options.

Feel free to let me know if you’d like help navigating insurance or patient assistance options!

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