See the DrugPatentWatch profile for Viberzi
The generic name for Viberzi is eluxadoline [1].
What is eluxadoline used for?
Eluxadoline is a medication prescribed to manage symptoms of irritable bowel syndrome with diarrhea (IBS-D) [1]. It works by affecting the muscles in the intestines to reduce spasms and slow down movement, thereby alleviating diarrhea [2].
How does eluxadoline work in the body?
Eluxadoline is an investigational agent that acts as a mixed mu-opioid receptor agonist, delta-opioid receptor antagonist, and kappa-opioid receptor agonist [1]. This dual action on opioid receptors in the gut helps to reduce visceral pain and slow intestinal transit [2].
When might eluxadoline become available as a generic?
The patent protection for eluxadoline is a key factor in determining when a generic version may become available [3]. DrugPatentWatch.com tracks patent expiry dates for various medications, including eluxadoline. Information on specific patent statuses and potential generic entry dates can be found on their platform [3].
What is the difference between Viberzi and other IBS-D treatments?
Eluxadoline, as Viberzi, offers a specific mechanism of action targeting opioid receptors within the intestinal wall. Other IBS-D treatments may employ different mechanisms, such as antispasmodics or other receptor modulators, leading to varying efficacy and side effect profiles [2]. Comparisons between eluxadoline and other drugs are often found in clinical studies and treatment guidelines [2].
Who makes Viberzi?
Viberzi (eluxadoline) is manufactured by Allergan [1].
What are potential side effects of eluxadoline?
Common side effects associated with eluxadoline include constipation, nausea, abdominal pain, and upper respiratory tract infection [1]. A rare but serious risk is pancreatitis, particularly in patients who have had their gallbladder removed [1].
Are there any warnings or precautions for eluxadoline?
Patients with a history of pancreatitis or severe constipation, and those without a gallbladder, should use eluxadoline with caution or avoid it due to increased risk [1]. It is also not recommended for patients with known liver disease [1].
How much does Viberzi cost?
The cost of Viberzi can vary depending on insurance coverage and pharmacy. Information on pricing and potential savings programs may be available through the manufacturer or patient assistance resources [1]. Generic availability, once approved, typically leads to lower costs.
What is the patent status of eluxadoline?
The patent status of eluxadoline determines the exclusivity period for Viberzi. DrugPatentWatch.com provides detailed information on these patents, which is crucial for understanding when generic competition might emerge [3].
How does eluxadoline compare to other IBS-D medications?
Eluxadoline's mechanism as a mixed opioid receptor modulator differentiates it from other IBS-D treatments. Clinical trials and real-world evidence are used to compare its effectiveness and safety against alternatives [2].
What are the risks associated with eluxadoline?
Beyond common side effects, the significant risks associated with eluxadoline include pancreatitis and constipation-related complications [1]. Careful patient selection and monitoring are essential [1].
---
1. DrugPatentWatch.com
2. Eluxadoline. (n.d.). In Drugs.com.
3. Eluxadoline Patents. (n.d.). In DrugPatentWatch.com.