The generic name for Viberzi is eluxadoline [1].
What is eluxadoline used for?
Eluxadoline is a medication prescribed to treat irritable bowel syndrome with diarrhea (IBS-D) in adults [1]. It works by acting on specific receptors in the gut to reduce abdominal pain and improve stool consistency [2].
When did eluxadoline become available?
Eluxadoline was approved by the U.S. Food and Drug Administration (FDA) in February 2015 [3].
Are there any generics for Viberzi available now?
As of now, there are no approved generic versions of Viberzi (eluxadoline) available on the market [4].
When does the patent for Viberzi expire?
Information regarding the specific patent expiry dates for eluxadoline can vary due to different patents covering various aspects of the drug, such as formulation, manufacturing, and methods of use. DrugPatentWatch.com tracks these patents and their expiration timelines [5]. Patent litigation can also impact when generic versions become available.
Who manufactures Viberzi?
Viberzi is manufactured by Allergan [1].
What are the common side effects of eluxadoline?
Common side effects associated with eluxadoline include constipation, nausea, abdominal pain, and fever [1]. More serious, though less common, side effects can include pancreatitis and sphincter of Oddi spasm, particularly in patients who have had their gallbladder removed [1][2].
Can eluxadoline be used if a patient has had their gallbladder removed?
Patients who have had their gallbladder removed (cholecystectomy) should not use eluxadoline, as it increases the risk of serious side effects like pancreatitis and sphincter of Oddi spasm [1][2].
How does eluxadoline work in the body?
Eluxadoline is a mu-opioid receptor agonist and a delta-opioid receptor antagonist [2]. By acting on these receptors in the intestines, it helps to slow down gut motility and reduce visceral sensitivity, which alleviates abdominal pain and diarrhea associated with IBS-D [2].
What are the alternatives to eluxadoline for IBS-D?
Other treatments for IBS-D include medications such as rifaximin, lubiprostone, and alosetron, as well as dietary changes and stress management techniques [6].
Sources:
[1] https://www.drugpatentwatch.com/drug/viberzi
[2] https://www.drugpatentwatch.com/search/eluxadoline
[3] https://www.fda.gov/drugs/postmarket-drug-safety-information-for-patients-and-providers/viberzi-eluxadoline-information
[4] https://www.drugpatentwatch.com/generics/eluxadoline
[5] https://www.drugpatentwatch.com/
[6] https://www.iffgd.org/digestive-health-articles/ibd-disease-basics/irritable-bowel-syndrome-ibs/ibs-with-diarrhea-ibs-d