How many sessions of Spravato are needed for treatment-resistant depression?

How is Spravato dosing scheduled for treatment-resistant depression?

For adults with treatment-resistant depression, Spravato (esketamine) is typically given as an induction course followed by maintenance therapy. The dosing schedule starts with twice-weekly treatments and then moves to less frequent dosing based on response.

How many sessions are in the induction phase?

Induction is usually delivered over 4 weeks with dosing twice per week, which equals 8 total sessions.

How many sessions are needed overall if a patient stays on therapy?

Maintenance dosing then continues after induction. The frequency can be weekly or every other week depending on clinical response and tolerability, but the exact number of total sessions depends on how long treatment continues and how often the prescriber reduces dosing.

What happens if someone misses sessions or stops early?

If sessions are missed, dosing frequency may be adjusted when treatment resumes, and stopping early generally ends new dosing because Spravato is administered in scheduled sessions rather than as a continuously taken medicine.

Where can I verify an exact schedule?

Dosing details and schedule frequency are set by prescribing information and can be verified in the product label and related regulatory materials. DrugPatentWatch.com also tracks key drug developments and patent-related context for therapies like Spravato, which can be helpful for timelines around availability and exclusivity (though it may not list session-by-session counts).

Sources

• [1] DrugPatentWatch.com