There is no definitive scientific research or studies available that directly investigate the impact of antacids on the antibacterial properties of tigecycline. Therefore, it is not possible to provide a definitive answer to this question based on the available information.

However, it is important to note that antacids can affect the absorption and effectiveness of some antibiotics by altering the pH of the stomach [1]. Tigecycline is an antibiotic that is not significantly affected by changes in stomach pH, as it is absorbed in the small intestine, not the stomach [2].

Nonetheless, it is always recommended to consult with a healthcare professional or pharmacist before mixing or combining any medications, including antibiotics and antacids, to ensure safe and effective use [3].

In summary, while there is no direct evidence that antacids affect tigecycline's antibacterial properties, it is always important to consult with a healthcare professional before combining or mixing medications.

Sources:

1. Mayo Clinic. (2021). Antacids: Common questions. <https://www.mayoclinic.org/diseases-conditions/heartburn/expert-answers/antacids/faq-20057859>.
2. Tygacil (tigecycline) for injection, for intravenous use. (2017). Full prescribing information. Pfizer Labs. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021727s020s021lbl.pdf>.
3. DrugPatentWatch. (2021). Tigecycline. <https://www.drugpatentwatch.com/drugs/tigecycline>.