Mefenamic acid injection?

Mefenamic acid injection is a short-acting NSAID used to relieve moderate pain quickly, usually in a clinical setting. It’s given by intramuscular (IM) injection; sometimes a second dose is given after several hours if needed. It’s intended for short-term use only.

Key points:
- Usual adult dosing (IM): 500 mg as a single dose, may repeat after about 6 hours if needed. Do not exceed 1,500 mg in 24 hours.
- Common uses: short-term relief of pain (e.g., menstrual cramps, postoperative pain, musculoskeletal pain).
- Onset: relief can begin within 30–60 minutes after the injection.
- Duration: intended for brief use; not a long-term pain-control option.

Safety and precautions:
- Contraindications: active stomach/intestinal ulcers or bleeding; history of GI bleeding/ulcers; known allergy to mefenamic acid or other NSAIDs; severe kidney, liver, or heart problems; pregnancy (especially after 20 weeks) unless advised by a clinician; certain bleeding disorders.
- Cautions: risk of GI side effects (nausea, vomiting, upset stomach), headaches, dizziness; can raise blood pressure or cause fluid retention; may worsen kidney function; rare serious liver or skin reactions.
- Interactions: increases bleeding risk with anticoagulants and other NSAIDs; may affect kidney function with diuretics or ACE inhibitors; may interact with steroids, lithium, methotrexate, or alcohol.
- Pregnancy/lactation: generally avoided during pregnancy (especially later stages) and breastfeeding; discuss alternatives with your clinician.

If you were prescribed this, follow the exact dosing on your prescription label. If you’re considering it for yourself or someone else and have health conditions (like ulcers, kidney disease, or are pregnant), or are taking other medicines, talk to a healthcare professional first.

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