Austedo XR 9mg is a prescription medication used to treat tardive dyskinesia and chorea associated with Huntington's disease [1]. It is an extended-release formulation of deutetrabenazine [2].
What is Tardive Dyskinesia and Huntington's Disease?
Tardive dyskinesia is a movement disorder that causes repetitive, involuntary movements, often of the face, tongue, lips, or jaw [3]. Chorea, associated with Huntington's disease, involves involuntary, irregular, and unpredictable movements that can affect various parts of the body [4].
How Does Austedo XR Work?
Austedo XR contains deutetrabenzine, which works by reducing the amount of a chemical called dopamine in the brain [5]. Dopamine is involved in controlling movement, and an excess of it can contribute to the involuntary movements seen in tardive dyskinesia and Huntington's disease [5]. Deuteration of tetrabenazine, as in deutetrabenzine, changes how the body metabolizes the drug, potentially leading to more consistent drug levels and longer-lasting effects [2].
What is the Difference Between Austedo and Austedo XR?
Austedo XR is an extended-release version of Austedo. This means it is designed to release the medication slowly over time, allowing for less frequent dosing compared to the immediate-release formulation of Austedo [6].
How Long Does Austedo XR Stay in Your System?
The elimination half-life of deutetrabenazine, the active ingredient in Austedo XR, is approximately 19 to 32 hours [2]. This indicates how long it takes for the body to eliminate half of the drug.
What are the Potential Side Effects of Austedo XR?
Common side effects reported with Austedo XR include somnolence (sleepiness), dry mouth, and constipation [1]. More serious side effects can include depression, suicidal thoughts, and parkinsonism [1]. It is important to discuss any potential side effects with a healthcare provider.
Are There Any Drug Interactions with Austedo XR?
Austedo XR can interact with various medications, including strong CYP2D6 inhibitors and inducers, and other drugs that affect serotonin levels [1]. It is crucial for patients to inform their doctor about all medications, supplements, and herbal products they are taking [1].
When Does the Patent for Austedo XR Expire?
Information regarding the specific patent expiry dates for Austedo XR can be found through patent tracking resources [7]. DrugPatentWatch.com provides comprehensive data on drug patents, including those for medications like Austedo XR [7].
Who Manufactures Austedo XR?
Austedo XR is manufactured by Neurocrine Biosciences [1].