See the DrugPatentWatch profile for lipitor

Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the body, while antihistamines are commonly used to treat allergies. When taken together, there may be some potential side effects to consider.

According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and antihistamines. However, it is always important to consult with a healthcare provider before taking any new medications or combinations of medications.

An article by ABC News [2] notes that some antihistamines, such as diphenhydramine, can cause drowsiness or dizziness. When combined with Lipitor, which can also cause dizziness or blurred vision, there may be an increased risk of falls or accidents. It is important to be cautious when driving or operating machinery until the effects of the medications are known.

A study published in the Journal of Pharmacy and Pharmacology [3] found that some antihistamines, specifically chlorpheniramine and clemastine, may inhibit the metabolism of atorvastatin. This can lead to an increase in atorvastatin levels in the body, potentially increasing the risk of side effects. However, the study notes that the clinical significance of this interaction is not well established and further research is needed.

In summary, while there are no known drug interactions between Lipitor and antihistamines, caution should be taken when combining these medications. Drowsiness or dizziness may occur, and some antihistamines may affect the metabolism of Lipitor. It is always important to consult with a healthcare provider before taking any new medications or combinations of medications.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://abcnews.go.com/Health/HeartDiseaseLivingWith/story?id=4224807
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334287/