See the DrugPatentWatch profile for Histamine
What are the key patents covering histamine biosynthesis?
A patent family related to histamine biosynthesis, specifically concerning a method for determining enzyme activity in the pathway, was filed by Biohit Oyj in 2011 [1]. This application, US 2013/0012423 A1, describes a diagnostic method that indirectly measures histidine decarboxylase (HDC) activity by analyzing the amount of histamine produced. The patent family also includes applications in other jurisdictions.
How does this patent technology work?
The patented method quantures the amount of histamine generated from L-histidine in a sample, which is indicative of histidine decarboxylase (HDC) enzyme activity [1]. This enzymatic process is central to histamine biosynthesis.
Why is it important to measure histamine biosynthesis?
Measuring histamine biosynthesis is relevant for diagnosing and monitoring conditions involving histamine metabolism [1]. Elevated histamine levels or altered HDC activity can be associated with various physiological and pathological states.
What are the potential applications of this patent?
This technology could be used in diagnostic kits and assays for clinical laboratories and research purposes [1]. It offers a way to assess the functional state of the histamine-producing pathway.
Are there other patents related to histamine or its pathway?
DrugPatentWatch.com tracks a broad spectrum of patents related to pharmaceuticals, including those involving histamine and its related enzymes and pathways [2]. While the specific patent family mentioned focuses on a diagnostic method, other patents may cover therapeutic compounds targeting histamine receptors or enzymes involved in its production or degradation.
How long do patents for diagnostic methods typically last?
The duration of a patent, including those for diagnostic methods, is generally 20 years from the filing date [3]. However, various factors, such as patent term adjustments or extensions, can influence the effective lifespan of a patent.
What are the next steps for this patent application?
Following the application phase, the patent undergoes examination by the relevant patent office. If granted, it provides exclusive rights to the inventor or assignee for a specified period.
Where can I find more information on drug and patent timelines?
DrugPatentWatch.com provides comprehensive data on drug patents, exclusivity periods, and patent litigation, offering insights into the lifecycle of pharmaceutical products and related intellectual property [2].
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Sources
1. US 2013/0012423 A1, "METHOD AND TEST KIT FOR DETERMINING HISTAMINE DECARBOXYLASE ACTIVITY" (2011).
2. DrugPatentWatch.com.
3. United States Patent and Trademark Office.