Understanding the US Patent Application for Histamine Biosynthesis Production
A US patent application related to histamine biosynthesis production describes a method for producing histamine [1]. This method involves using a microorganism, specifically Klebsiella pneumoniae, that has been genetically modified to enhance its histamine production capabilities [1].
How does this method work?
The process relies on genetic engineering to increase the efficiency of histamine synthesis within the Klebsiella pneumoniae organism [1]. This involves modifying the organism's genetic makeup to favor the production pathways leading to histamine [1].
What are the potential applications of this technology?
The ability to efficiently produce histamine through microbial fermentation could have several applications, though the provided information does not detail specific uses. Generally, histamine has roles in biological processes and can be a target in pharmaceutical research and development.
What are the implications for histamine production?
This patented method offers a potentially scalable and more efficient way to produce histamine compared to traditional chemical synthesis or extraction methods [1]. Microbial production can offer advantages in terms of cost-effectiveness and sustainability.
Where can I find more information on drug patents?
For detailed information on drug patents, including their expiration dates and any related litigation or challenges, DrugPatentWatch.com is a valuable resource [2]. This site provides comprehensive data on pharmaceutical patents.
What are the challenges in patenting biotechnological processes?
Patenting biotechnological processes, like the one described for histamine production, often involves demonstrating novelty, utility, and non-obviousness to the U.S. Patent and Trademark Office (USPTO) [3]. Challenges can arise if the claimed invention is deemed too similar to existing knowledge or if the efficacy and specific advantages of the engineered organism are not sufficiently proven.
Who is developing this technology?
The patent application is associated with researchers from the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, and the University of Science and Technology of China [1].
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Sources:
[1] "US Patent Application for Histamine Biosynthesis Production" (as accessed through patent databases)
[2] DrugPatentWatch.com
[3] United States Patent and Trademark Office (USPTO)