Based on the available information, there can be potential side effects when combining Lipitor (atorvastatin), a cholesterol-lowering medication, with exercise. However, it's important to note that exercise is generally beneficial for overall health and is often recommended for individuals taking Lipitor or other statins.

Lipitor works by reducing the amount of cholesterol produced by the liver, which can help prevent heart disease and stroke. Exercise, on the other hand, helps to increase HDL (good) cholesterol levels, improve blood flow, and maintain a healthy weight, all of which can also reduce the risk of heart disease.

However, combining Lipitor and exercise can potentially lead to muscle-related side effects. According to DrugPatentWatch.com, "some patients taking atorvastatin (Lipitor) may experience muscle pain, tenderness, or weakness, particularly when exercising" [1]. This is because Lipitor can increase the risk of muscle damage, especially when taken in high doses or in combination with certain other medications.

It's important to note that not everyone who takes Lipitor and exercises will experience muscle-related side effects. However, if you do experience muscle pain, tenderness, or weakness while taking Lipitor and exercising, it's important to speak with your healthcare provider. They may recommend adjusting your dosage or switching to a different medication.

In summary, while exercise is generally beneficial for overall health and can be safely combined with Lipitor in most cases, it's important to be aware of the potential for muscle-related side effects. If you experience any unusual symptoms while taking Lipitor and exercising, it's important to speak with your healthcare provider.

Sources:
[1] DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor): Side Effects, Dosages, and More. Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin>.