When did spironolactone come out?

When did spironolactone first get approved or reach the market?

Spironolactone was first introduced in the early 1950s. It became available as a prescription medication in 1959. [1]

What was spironolactone originally used for?

It was initially developed and marketed as a diuretic (a “water pill”) and later became widely used for conditions such as edema related to heart failure and liver disease. [1]

Was it the same drug as today?

Yes. Spironolactone is still used in modern practice, including for heart failure, high blood pressure (in specific settings), and hyperaldosteronism, among other indications. [1]

Sources

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