Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the blood [1]. Antihistamines, on the other hand, are a class of drugs used to treat allergic reactions and symptoms [2]. While there is no known interaction between Lipitor and antihistamines, it is still recommended to take them at different times to avoid any potential side effects or reduced effectiveness of either medication [3].

According to the NHS, statins such as Lipitor should be taken at the same time each day, preferably in the evening, as this is when the body produces the most cholesterol [2]. Antihistamines, on the other hand, can be taken at any time of day, but it is recommended to take them before bedtime if they cause drowsiness [2].

It is important to note that different types of antihistamines may have different effects on the body, and some may interact with other medications. Therefore, it is always best to consult with a healthcare provider before taking any new medications or combining medications [3].

In conclusion, while there is no known interaction between Lipitor and antihistamines, it is still recommended to take them at different times to avoid any potential side effects or reduced effectiveness of either medication. Lipitor should be taken at the same time each day, preferably in the evening, while antihistamines can be taken at any time of day, but it is recommended to take them before bedtime if they cause drowsiness. As with any medication, it is always best to consult with a healthcare provider before taking any new medications or combining medications.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.nhs.uk/conditions/statins/considerations/
[3] https://www.verywellhealth.com/statin-side-effects-and-drug-interactions-698202