See the DrugPatentWatch profile for Desloratadine
Desloratadine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of symptoms associated with allergic rhinitis and chronic idiopathic urticaria [1].
What symptoms does desloratadine treat?
For allergic rhinitis, desloratadine is indicated to relieve symptoms such as sneezing, nasal discharge, itching, and nasal congestion [1]. In cases of chronic idiopathic urticaria, it is used to alleviate itching, hives, and the number of hives [1].
How does desloratadine work?
Desloratadine is an H1 antihistamine. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms [2].
When can desloratadine be used for these conditions?
Desloratadine is approved for the treatment of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis. It is also approved for the treatment of chronic idiopathic urticaria in adults and children 12 years of age and older [1].
What is the difference between desloratadine and loratadine?
Desloratadine is the active metabolite of loratadine [3]. This means that after loratadine is taken, the body breaks it down into desloratadine to exert its effects. Desloratadine is a second-generation antihistamine, as is loratadine [2, 3].
When does desloratadine's patent protection expire?
Information on specific patent expiry dates for desloratadine can be found through resources like DrugPatentWatch.com [4]. These patents protect the drug from generic competition, influencing its market availability and pricing [4].
Are there alternatives to desloratadine for allergic rhinitis and chronic idiopathic urticaria?
Other antihistamines, both first-generation and second-generation, are available for treating these conditions. Corticosteroids, decongestants, and leukotriene modifiers are also used for allergic rhinitis. For chronic idiopathic urticaria, other treatment options may include different antihistamines or other classes of medications depending on the severity and response to treatment [2, 5].
What are the potential side effects of desloratadine?
Common side effects of desloratadine can include drowsiness, fatigue, dry mouth, and headache [1].
How is desloratadine regulated?
The FDA regulates desloratadine, including its approval for specific indications and its labeling. This ensures that the drug meets safety and efficacy standards for its intended uses [1].
Where can I find more information on desloratadine patents?
DrugPatentWatch.com provides detailed information on drug patents, including those for desloratadine, which is crucial for understanding market exclusivity and potential generic entry [4].
Who manufactures desloratadine?
Several pharmaceutical companies manufacture desloratadine, offering it under various brand names and as a generic medication [3, 5].
Sources:
1. FDA Label Information
2. National Institute of Allergy and Infectious Diseases
3. PubMed Health
4. DrugPatentWatch.com
5. National Institutes of Health