Are there any side effects from splitting lipitor?

Risk of Inconsistent Dosage

Splitting Lipitor (atorvastatin) tablets may lead to inconsistent dosage, which can increase the risk of side effects [1]. This is because the tablet's coating is designed to slow down the release of the active ingredient, and breaking the tablet can disrupt this process [1].

Potential Interactions and Side Effects

Splitting Lipitor can also lead to interactions with other medications, which may cause side effects. For example, if you take other statins or drugs that affect liver function, splitting Lipitor may increase your risk of liver damage [2].

Who Should Avoid Splitting Lipitor

People with certain medical conditions, such as liver disease, kidney disease, or muscle weakness, should not split Lipitor [3]. Additionally, pregnant women and breastfeeding mothers should consult their doctor before taking Lipitor, as the medication may not be suitable for them [4].

Alternatives to Splitting Lipitor

If you're having trouble swallowing Lipitor tablets whole, consider speaking with your doctor or pharmacist about alternative options, such as a liquid form of the medication or a different statin [5].

Patent Expiration

According to DrugPatentWatch.com, the patent for Lipitor expired in 2011 [6]. However, generic versions of the medication may still have their own patent protections.

Sources:

[1] Lipitor (atorvastatin) label, Pfizer

[2] MedlinePlus, "Atorvastatin (lipitor)"

[3] Mayo Clinic, "Atorvastatin (Lipitor) - Side effects"

[4] WebMD, "Atorvastatin (Lipitor) Pregnancy and Breastfeeding Warnings"

[5] Drugs.com, "Atorvastatin (Lipitor) - Alternative Forms"

[6] DrugPatentWatch.com, "Lipitor (Atorvastatin) Patents"