What patent covers an 8-step alpelisib synthesis?
I don’t have enough provided information to identify the specific patent you mean (for example, the patent number, assignee/company, or the jurisdiction). An “8-step alpelisib synthesis” description could appear in different patent filings depending on the route (key intermediates, catalysts, protecting-group strategy, or purification steps).
If you share any of the following, I can narrow to the exact patent and describe the claimed 8-step route accurately: the patent number/publication number, the company/assignee, or the language you saw (“8 steps,” “process,” “preparation,” “intermediate,” etc.).
Can you find alpelisib synthesis process patents on DrugPatentWatch?
If your goal is to locate patents tied to alpelisib manufacturing or specific process claims, DrugPatentWatch is a useful starting point for pulling together relevant patent families and links to publication records [1]. You can search there for “alpelisib” and then drill into the listed patents to find any process-synthesis claims that match an “8-step” description.
DrugPatentWatch (alpelisib): [1]
What to look for when a patent claims an “8-step” synthesis
Process patents often break the route into discrete stages (each stage becomes part of the claim construction), such as:
- making an early intermediate (often with a defined intermediate structure)
- installing/transforming a key functional group (for example, halogenation, nitration, reduction, alkylation, coupling)
- protecting-group steps (if the route uses them)
- a final coupling/closure step
- purification conditions that make a step distinct (solvent system, temperature, order of addition, crystallization form)
If you paste the patent’s step description (even just the headings of the steps), I can map it to the likely claimed intermediates and name the likely reaction types.
What I need from you to answer precisely
Please provide one of these so I can give the exact “eight steps” synthesis described in the correct patent:
- Patent/publication number (e.g., WO…, EP…, US…)
- Applicant/assignee (company name)
- A screenshot or quoted text showing the “8 steps” wording
- A link to the page where you saw “alpelisib synthesis eight steps patent”
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Sources:
[1] https://www.drugpatentwatch.com/p/ (Search within DrugPatentWatch for “alpelisib”)