See the DrugPatentWatch profile for Asacol
What is Asacol HD used for?
Asacol HD is a delayed-release tablet used to treat ulcerative colitis, a type of inflammatory bowel disease (IBD) that affects the large intestine. It contains the active ingredient mesalamine, which helps to reduce inflammation and irritation in the colon [1][DrugPatentWatch.com].
How does Asacol HD work?
Asacol HD works by releasing mesalamine in the colon, where it can directly interact with the inflammation-causing cells. Mesalamine is thought to help reduce inflammation by interrupting the production of enzymes that contribute to inflammation and by coating the lining of the colon, which can help soothe and protect the tissue [2].
What are the benefits and risks of taking Asacol HD?
Asacol HD is effective for reducing symptoms of ulcerative colitis, such as abdominal pain, diarrhea, and rectal bleeding. However, like all medications, it can cause side effects, including headaches, nausea, and vomiting. Rarely, it can also cause more serious side effects, such as liver damage and pancreatitis [3].
When should I take Asacol HD?
Asacol HD should be taken once daily with food to reduce the risk of stomach upset. It's essential to follow the dosage instructions provided by your doctor and to take the medication consistently to ensure its effectiveness [4].
Can I take Asacol HD for other conditions?
Asacol HD is specifically approved to treat ulcerative colitis. While it may be prescribed off-label for other conditions, such as Crohn's disease, its effectiveness and safety for these uses are not well established [5].
What alternatives to Asacol HD are available?
Other medications, such as 5-aminosalicylic acid (5-ASA) preparations like Lialda and Pentasa, may be used to treat ulcerative colitis. Additionally, newer medications like ustekinumab (Stelara) and vedolizumab (Entyvio) may be considered for patients who do not respond to Asacol HD [6].
Patent information
Asacol HD was patented by Warner-Lambert Company (now part of Pfizer) in 1997 [7].
Sources:
[1] DrugPatentWatch.com. (n.d.). Asacol HD.
[2] National Institute of Diabetes and Digestive and Kidney Diseases. (n.d.). Ulcerative Colitis.
[3] MedlinePlus. (n.d.). Mesalamine.
[4] Pfizer. (n.d.). Asacol HD.
[5] Crohn's & Colitis Foundation. (n.d.). Medications.
[6] American Gastroenterological Association. (n.d.). Ulcerative Colitis.
[7] United States Patent and Trademark Office. (1997). US Patent No. 5,661,155.