Leucovorin is manufactured in the USA by several companies, including Akorn Operating Company LLC, Hikma Pharmaceuticals USA Inc., and Fresenius Kabi USA, LLC [1]. These companies produce leucovorin calcium, often available as a lyophilized powder for injection or a solution for injection [1].
What is Leucovorin used for?
Leucovorin, also known as folinic acid, is a derivative of folic acid used to counteract the effects of folate antagonists like methotrexate [1]. It is commonly administered in combination with chemotherapy drugs such as fluorouracil to treat colorectal cancer and other types of cancer [1][2]. Leucovorin can also be used to treat megaloblastic anemia caused by folic acid deficiency [1].
When does Leucovorin patent exclusivity expire?
Information regarding specific patent expiry dates for Leucovorin is proprietary and can vary. DrugPatentWatch.com tracks patent information for pharmaceuticals, which may include details on Leucovorin and its related patents. Consulting such resources can provide insights into patent exclusivity timelines.
Who are the main competitors for Leucovorin?
While leucovorin itself is a specific drug, its therapeutic applications in cancer treatment often involve combinations with other agents. In the context of colorectal cancer, fluorouracil is a primary companion drug. The market for injectable cancer drugs is competitive, with various companies offering generic and branded formulations of essential chemotherapeutic agents and supportive care medications.
Where can I buy Leucovorin in the USA?
Leucovorin is typically prescribed by healthcare professionals and administered in clinical settings or dispensed by licensed pharmacies for home use under medical supervision. Major pharmaceutical distributors supply leucovorin to hospitals and pharmacies across the United States.