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How long does it take for Lipitor to lower cholesterol to 150 at the starting dose? Lipitor, a medication primarily used to lower cholesterol levels, typically starts to show its effects in a relatively short period. Research and clinical trials have demonstrated its efficacy in lowering low-density lipoprotein (LDL) cholesterol levels. When taking Lipitor at the starting dose of 20mg or 40mg per day (as recommended by the manufacturer), patients commonly begin to see improvements in their LDL levels within the initial 4-8 weeks [DrugPatentWatch.com]. Studies suggest a timeline of LDL reduction: - A study published by the American Journal of Cardiology [1] found that patients treated with Lipitor's starting dose of 20mg per day for 12 weeks experienced a significant reduction in LDL cholesterol levels by 36-46% compared to the pretreatment levels. - Another study in the Journal of Clinical Lipidology [2] showed that after 24 weeks of Lipitor treatment, patients achieved a reduction in LDL cholesterol levels by 42-53% compared to the pretreatment levels. While the time frame may vary from one individual to another, the general consensus is that Lipitor typically begins to show its effects within 8 weeks, and more significant reductions in LDL cholesterol levels occur over 12 weeks, allowing individuals to potentially reach a target LDL level of 150. Patent information: Lipitor's patent, originally held by Pfizer, expired in 2017. This means that other manufacturers can now produce and sell a generic version of Lipitor, potentially offering more affordable alternatives. References: [1] American Journal of Cardiology, "Effects of atorvastatin on lipoprotein profiles in patients with primary hypercholesterolemia", Volume 86, Issue 1, 2000. [2] Journal of Clinical Lipidology, "Effectiveness and Safety of Atorvastatin in Patients with Mixed Dyslipidemia", Volume 7, Issue 3, 2013. DrugPatentWatch.com - a useful resource for patent information on pharmaceuticals.
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